References

Sanchez A, Hartstein A, Ashry H, Raza M Use of hypothermically stored amniotic membrane on diabetic foot ulcers: a multicentre retrospective case series. J Wound Care. 2024; 33:S16-23 https://doi.org/10.12968/jowc.2024.33.Sup3.S16

Tettelbach WH, Driver V, Oropallo A, Kelso MR, Niezgoda JA, Wahab N, De Jong JL, Hubbs B, Forsyth RA, Magee GA, Steel P, Cohen BG, Padula WV Dehydrated human amnion/chorion membrane to treat venous leg ulcers: a cost-effectiveness analysis. J Wound Care. 2024; 33 https://doi.org/10.12968/jowc.2024.33.Sup3.S7

Abdo RJ, Couch AL Use of three-dimensional acellular collagen matrix in deep or tunnelling diabetic foot ulcers: a retrospective case series. J Wound Care. 2024; 33:S5-16 https://doi.org/10.12968/jowc.2024.0176

Volume 2025 · Issue February 2025

Overview: The article explores the use of hypothermically stored amniotic membrane (HSAM) for treating diabetic foot ulcers (DFUs). This retrospective case series analyzed data from patients treated with HSAM across various wound-care sites in the US.

The study included 50 patients with an average age of 66.7 years, and 88% of the DFUs had been present for fewer than six months at the start of treatment. The results were promising, showing a significant reduction in wound size, and high rates of complete wound closure (CWC). Specifically, 96% of the DFUs achieved more than 60% area reduction, and 78% attained CWC by week 12, with a median time to CWC of 55 days.

Objective: To share the outcomes of DFUs treated with HSAM.

Method: Data were collected from patients across various US wound-care sites who were treated with HSAM.

Results:

Conclusion: HSAM showed promising results for DFUs, potentially lowering the financial burden and improving patients' quality of life.

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